Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.

Cancer invasion and metastasis have been likened to wound healing gone awry. Despite parallels in cellular behavior between cancer progression and wound healing, the molecular relationships between these two processes and their prognostic implications are unclear. In this study, based on gene expres...

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Bibliographic Details
Main Authors: Howard Y Chang, Julie B Sneddon, Ash A Alizadeh, Ruchira Sood, Rob B West, Kelli Montgomery, Jen-Tsan Chi, Matt van de Rijn, David Botstein, Patrick O Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0020007