Molecular Mechanisms of KDELC2 on Glioblastoma Tumorigenesis and Temozolomide Resistance

The activation of the Notch pathway induces glioblastoma (GBM) development. Since KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2) is involved in the Notch pathway, the detailed mechanism is still undetermined. The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) databases revealed that...

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Bibliographic Details
Main Authors: Yu-Ling Tsai, Hsin-Han Chang, Ying-Chuan Chen, Yu-Chan Chang, Ying Chen and Wen-Chiuan Tsai
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/9/339