Enteric coated HPMC capsules plugged with 5-FU loaded microsponges: a potential approach for treatment of colon cancer

Enteric coated HPMC capsules plugged with 5-FU loaded microsponges: a potential approach for treatment of colon cancer

The work was aimed at developing novel enteric coated HPMC capsules (ECHC) plugged with 5 Florouracil (5-FU) loaded Microsponges in combination with calcium pectinate beads. Modified quasi-emulsion solvent diffusion method was used to formulate microsponges based on 32 factorial design and the effec...

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Bibliographic Details
Main Authors: Ankita Gupta, Gaurav Tiwari, Ruchi Tiwari, Rishabh Srivastava, A. K. Rai
Format: Article
Language:English
Published: Universidade de São Paulo 2015-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Fluoruracila
Cápsula de HPMC/revestimento entérico
Microesponjas/formulação
Fármaco/liberação/direcionamento para o cólon
Câncer colorretal/tratamento
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300591&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300591&lng=en&tlng=en

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