Genetic Variation of Kallikrein-Kinin System and Related Genes in Patients With Hereditary Angioedema

Genetic Variation of Kallikrein-Kinin System and Related Genes in Patients With Hereditary Angioedema

Hereditary angioedema (HAE) is an autosomal dominant disease caused by C1-INH deficiency due to mutations in SERPING1 (C1-INH-HAE) in most of the cases, or by specific mutations in factor XII gene, F12 (F12-HAE). Identification of polymorphisms in the genes encoding proteins from key pathways drivin...

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Bibliographic Details
Main Authors: Camila Lopes Veronez, Anne Aabom, Renan Paulo Martin, Rafael Filippelli-Silva, Rozana Fátima Gonçalves, Priscila Nicolicht, Agatha Ribeiro Mendes, Jane Da Silva, Mar Guilarte, Anete Sevciovic Grumach, Eli Mansour, Anette Bygum, João Bosco Pesquero
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Medicine
Subjects:
hereditary angioedema
Kallikrein-Kinin System
genetic variation
genotype-phenotype correlation
C1 inhibitor deficiency
F12 mutation
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00028/full

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https://www.frontiersin.org/article/10.3389/fmed.2019.00028/full

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