Immunodeficient mice are better for modeling the transfusion of human blood components than wild-type mice.
Animal models are vital to the study of transfusion and development of new blood products. Post-transfusion recovery of human blood components can be studied in mice, however, there is a need to identify strains that can best tolerate xenogeneic transfusions, as well as to optimize such protocols. S...
Main Authors: | Sophia A Blessinger, Johnson Q Tran, Rachael P Jackman, Renata Gilfanova, Jacqueline Rittenhouse, Alan G Gutierrez, John W Heitman, Kelsey Hazegh, Tamir Kanias, Marcus O Muench |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0237106 |
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