OCT4B1 Promoted EMT and Regulated the Self-Renewal of CSCs in CRC: Effects Associated with the Balance of miR-8064/PLK1

Cancer stem cells (CSCs) are the main cause of tumor generation, recurrence, metastasis, and therapy failure in various malignancies including colorectal cancer (CRC). Accumulating evidence suggests that tumor cells can acquire CSC characteristics through the epithelial-mesenchymal transition (EMT)...

Full description

Bibliographic Details
Main Authors: Jun-min Zhou, Shui-qing Hu, Hang Jiang, Yi-lin Chen, Ji-hong Feng, Zheng-quan Chen, Kun-ming Wen
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300750