Predialysis and Dialysis Therapies Differently Affect Nitric Oxide Synthetic Pathway in Red Blood Cells from Uremic Patients: Focus on Peritoneal Dialysis

Predialysis and Dialysis Therapies Differently Affect Nitric Oxide Synthetic Pathway in Red Blood Cells from Uremic Patients: Focus on Peritoneal Dialysis

Red blood cells (RBCs) have been found to synthesize and release both nitric oxide (NO) and cyclic guanosine monophosphate (cGMP), contributing to systemic NO bioavailability. These RBC functions resulted impaired in chronic kidney disease (CKD). This study aimed to evaluate whether predialysis (con...

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Bibliographic Details
Main Authors: Carola Palmerini, Luca Piscitani, Giuseppina Bologna, Chiara Riganti, Paola Lanuti, Domitilla Mandatori, Lorenzo Di Liberato, Giorgia Di Fulvio, Vittorio Sirolli, Giulia Renda, Caterina Pipino, Marco Marchisio, Mario Bonomini, Assunta Pandolfi, Natalia Di Pietro
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
erythrocytes
chronic kidney disease
nitric oxide
cGMP
cardiovascular disease
MRP4
Online Access:https://www.mdpi.com/1422-0067/22/6/3049

Internet

https://www.mdpi.com/1422-0067/22/6/3049

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