The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System

The protein p63 has been identified as a homolog of the tumor suppressor protein p53 and is capable of inducing apoptosis, cell cycle arrest, or senescence. p63 has at least six isoforms, which can be divided into two major groups: the TAp63 variants that contain the N-terminal transactivation domai...

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Bibliographic Details
Main Authors: Stephen R. Armstrong, Hong Wu, Benfan Wang, Yasser Abuetabh, Consolato Sergi, Roger P. Leng
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
p63
Online Access:http://www.mdpi.com/1422-0067/17/12/2041