Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise

Abstract With the increasing number of therapeutic strategies tested in humans to reduce the size of the latent reservoir, the development of a robust, precise and clinical trial scalable assay that measures the frequency of infected cells carrying inducible replication-competent HIV is urgently nee...

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Bibliographic Details
Main Authors: Johann Plantin, Marta Massanella, Nicolas Chomont
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Retrovirology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12977-017-0385-y