Comparison of serum fractionation methods by data independent label-free proteomics

Off-line sample prefractionations applied prior to biomarker discovery proteomics are options to enable more protein identifications and detect low-abundance proteins. This work compared five commercial methods efficiency to raw serum analysis using label-free proteomics. The variability of the prot...

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Bibliographic Details
Main Authors: D. Baiwir, G. Mazzucchelli, N. Smargiasso, F. Quesada-Calvo, E. De Pauw, M. Malaise, E. Louis, M.-A. Meuwis
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:EuPA Open Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968515300118