Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells

Survivin selective inhibitor YM155 induce apoptosis in SK-NEP-1 Wilms tumor cells

<p>Abstract</p> <p>Background</p> <p>Survivin, a member of the family of inhibitor of apoptosis proteins, functions as a key regulator of mitosis and programmed cell death. YM155, a novel molecular targeted agent, suppresses survivin, which is overexpressed in many tumo...

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Bibliographic Details
Main Authors: Tao Yan-Fang, Lu Jun, Du Xiao-Juan, Sun Li-Chao, Zhao Xuan, Peng Liang, Cao Lan, Xiao Pei-Fang, Pang Li, Wu Dong, Wang Na, Feng Xing, Li Yan-Hong, Ni Jian, Wang Jian, Pan Jian
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Cancer
Subjects:
YM155
SK-NEP-1
Survivin
Apoptosis
Real-time PCR array
Online Access:http://www.biomedcentral.com/1471-2407/12/619

Internet

http://www.biomedcentral.com/1471-2407/12/619

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