Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and six weeks of exercise in obese female mice

Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and six weeks of exercise in obese female mice

Obesity is well known to be a major cause of several chronic metabolic diseases, which can be partially counteracted by exercise. This is due, in part, to an upregulation of mitochondrial activity through increased nicotinamide adenine dinucleotide (NAD+). Recent studies have shown that NAD+ levels...

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Bibliographic Details
Main Authors: Golam Mezbah Uddin, Neil A Youngson, David A Sinclair, Margaret J Morris
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Pharmacology
Subjects:
Liver
Mitochondria
Nicotinamide Mononucleotide
Muscle
high fat diet
treadmill exercise
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00258/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00258/full

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