Gambogic Acid Efficiently Kills Stem-Like Colorectal Cancer Cells by Upregulating ZFP36 Expression

Gambogic Acid Efficiently Kills Stem-Like Colorectal Cancer Cells by Upregulating ZFP36 Expression

Background/Aims: Gambogic acid (GA), the main active compound of Gamboge hanburyi, has been reported to be a potential novel antitumor drug. Whether GA inhibits putative cancer stem cells (CSCs), which are considered to be the major cause of cancer treatment failure, remains largely unknown. This st...

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Bibliographic Details
Main Authors: Fang Wei, Tong Zhang, Zhi Yang, Jian-Chang Wei, Hong-Fen Shen, Dong Xiao, Qiang Wang, Ping Yang, Hua-Cui Chen, He Hu, Zhuan-Peng Chen, Qing Huang, Wang-Lin Li, Jie Cao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Colorectal carcinoma
Gambogic acid
Cancer stem cells
Promoter-reporter gene strategy
ZFP36
In vivo bioluminescence imaging
Online Access:https://www.karger.com/Article/FullText/488740

Internet

https://www.karger.com/Article/FullText/488740

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