Autophagy is Activated <i>In Vivo</i> during Trimethyltin-Induced Apoptotic Neurodegeneration: A Study in the Rat Hippocampus

Trimethyltin (TMT) is an organotin compound known to produce significant and selective neuronal degeneration and reactive astrogliosis in the rodent central nervous system. Autophagy is the main cellular mechanism for degrading and recycling protein aggregates and damaged organelles, which in differ...

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Bibliographic Details
Main Authors: Sabrina Ceccariglia, Alessandra Alvino, Aurora Del Fà, Ornella Parolini, Fabrizio Michetti, Carlo Gangitano
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/1/175