The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity.

COVID-19 outbreak is the biggest threat to human health in recent history. Currently, there are over 1.5 million related deaths and 75 million people infected around the world (as of 22/12/2020). The identification of virulence factors which determine disease susceptibility and severity in different...

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Bibliographic Details
Main Authors: Carlos Ramirez Alvarez, Carmon Kee, Ashwini Kumar Sharma, Leonie Thomas, Florian I Schmidt, Megan L Stanifer, Steeve Boulant, Carl Herrmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009687