Recurrent DMD Deletions Highlight Specific Role of Dp71 Isoform in Soft-Tissue Sarcomas

Soft-tissue sarcomas (STS) are rare tumors whose oncogenesis remains unknown and for which no common therapeutic target has yet been identified. Analysis of 318 STS by CGH array evidenced a frequent deletion affecting the <i>DMD</i> gene (encoding dystrophin isoforms) in 16.5% of STS, in...

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Bibliographic Details
Main Authors: Olivier Mauduit, Vanessa Delcroix, Tom Lesluyes, Gaëlle Pérot, Pauline Lagarde, Lydia Lartigue, Jean-Yves Blay, Frédéric Chibon
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
DMD
Online Access:https://www.mdpi.com/2072-6694/11/7/922