Development of Triptolide Self-Microemulsifying Drug Delivery System and Its Anti-tumor Effect on Gastric Cancer Xenografts

Development of Triptolide Self-Microemulsifying Drug Delivery System and Its Anti-tumor Effect on Gastric Cancer Xenografts

Purpose: To develop a triptolide (TP) self-microemulsifying drug delivery system and to investigate its anti-tumor effect on human gastric cancer line MGC80-3 xenografts in nude mice.Methods: The medium chain triglyceride (MCT) was selected as oil phase; polyoxyethylene castor oil (EL) was selected...

Full description

Bibliographic Details
Main Authors: Minghua Xie, Jia Wu, Liqaing Ji, Xiaorui Jiang, Jin Zhang, Min Ge, Xinjun Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
triptolide
self-microemulsifying delivery system
central composite design and response surface methodology
MGC80-3 cells
anti-tumor effect
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00978/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00978/full

Similar Items