Combination strategies to overcome resistance to the BCL2 inhibitor venetoclax in hematologic malignancies
Abstract Venetoclax has been approved by the United States Food and Drug Administration since 2016 as a monotherapy for treating patients with relapsed/refractory chronic lymphocytic leukemia having 17p deletion. It has led to a breakthrough in the treatment of hematologic malignancies in recent yea...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-10-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-020-01614-z |