Tumor necrosis factor-α regulates glucocorticoid synthesis in the adrenal glands of Trypanosoma cruzi acutely-infected mice. the role of TNF-R1.

Tumor necrosis factor-α regulates glucocorticoid synthesis in the adrenal glands of Trypanosoma cruzi acutely-infected mice. the role of TNF-R1.

Adrenal steroidogenesis is under a complex regulation involving extrinsic and intrinsic adrenal factors. TNF-α is an inflammatory cytokine produced in response to tissue injury and several other stimuli. We have previously demonstrated that TNF-R1 knockout (TNF-R1(-/-)) mice have a dysregulated synt...

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Bibliographic Details
Main Authors: Silvina R Villar, M Teresa Ronco, Rodrigo Fernández Bussy, Eduardo Roggero, Ailin Lepletier, Romina Manarin, Wilson Savino, Ana Rosa Pérez, Oscar Bottasso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3661674?pdf=render

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http://europepmc.org/articles/PMC3661674?pdf=render

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