Familial Atypical Hemolytic Uremic Syndrome: A Review of Its Genetic and Clinical Aspects

Atypical hemolytic uremic syndrome (aHUS) is a rare renal disease (two per one million in the USA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Both sporadic (80% of cases) and familial (20% of cases) forms are recognized. The study of familial aHUS...

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Bibliographic Details
Main Authors: Fengxiao Bu, Nicolo Borsa, Ardissino Gianluigi, Richard J. H. Smith
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/370426