Delirium Accompanied by Cholinergic Deficiency and Organ Failure in a 73-Year-Old Critically Ill Patient: Physostigmine as a Therapeutic Option

Delirium is a common problem in ICU patients, resulting in prolonged ICU stay and increased mortality. A cholinergic deficiency in the central nervous system is supposed to be a relevant pathophysiologic process in delirium. Acetylcholine is a major transmitter of the parasympathetic nervous system...

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Bibliographic Details
Main Authors: Benedikt Zujalovic, Eberhard Barth
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2015/793015