Paclitaxel Increases High Voltage–Dependent Calcium Channel Current in Dorsal Root Ganglion Neurons of the Rat

Peripheral neuropathic pain is a serious side effect of paclitaxel treatment. However, the mechanism of this paclitaxel-induced neuropathic pain is unknown. In this study, we investigated the effects of paclitaxel on the voltage-dependent calcium channel (VDCC) current in rat dorsal root ganglion (D...

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Bibliographic Details
Main Authors: Kazuyoshi Kawakami, Terumasa Chiba, Nobuyuki Katagiri, Maya Saduka, Kenji Abe, Iku Utsunomiya, Toshihiro Hama, Kyoji Taguchi
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319304335