Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate.

Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate.

The enzyme ribonucleotide reductase (RNR) catalyzes the conversion of ribonucleotides to deoxyribonucleotides, the precursors for DNA. RNR requires a thiyl radical to activate the substrate. In RNR of eukaryotes (class Ia RNR), this radical originates from a tyrosyl radical formed in reaction with o...

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Bibliographic Details
Main Authors: Guro K Sandvik, Ane B Tomter, Jonas Bergan, Giorgio Zoppellaro, Anne-Laure Barra, Asmund K Røhr, Matthias Kolberg, Stian Ellefsen, K Kristoffer Andersson, Göran E Nilsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3419237?pdf=render

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http://europepmc.org/articles/PMC3419237?pdf=render

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