The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.

Deciphering the mechanisms regulating the generation of new neurons and new oligodendrocytes, the myelinating cells of the central nervous system, is of paramount importance to address new strategies to replace endogenous damaged cells in the adult brain and foster repair in neurodegenerative diseas...

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Main Authors: Davide Lecca, Maria Letizia Trincavelli, Paolo Gelosa, Luigi Sironi, Paolo Ciana, Marta Fumagalli, Giovanni Villa, Claudia Verderio, Carlotta Grumelli, Uliano Guerrini, Elena Tremoli, Patrizia Rosa, Serena Cuboni, Claudia Martini, Annalisa Buffo, Mauro Cimino, Maria P Abbracchio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18974869/pdf/?tool=EBI