Preparation, characterization, and dissolution studies of naproxen solid dispersions using polyethylene glycol 6000 and labrafil M2130

Naproxen is a poor water soluble, non-steroidal analgesic and anti-inflammatory drug. The enhancement of oral bioavailability of poor water soluble drugs remains one of the most challenging aspects of drug development. Although salt formation, solubilization and particle size reduction have commonly...

Full description

Bibliographic Details
Main Authors: Jafar Akbari, Reza Enayatifard, Majid Saeedi, Katayoun Morteza-Semnani, Samira Rajabi
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2015-06-01
Series:Pharmaceutical and Biomedical Research
Subjects:
Online Access:http://pbr.mazums.ac.ir/browse.php?a_code=A-10-26-15&slc_lang=en&sid=1