LRScaf: improving draft genomes using long noisy reads

Abstract Background The advent of third-generation sequencing (TGS) technologies opens the door to improve genome assembly. Long reads are promising for enhancing the quality of fragmented draft assemblies constructed from next-generation sequencing (NGS) technologies. To date, a few algorithms that...

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Bibliographic Details
Main Authors: Mao Qin, Shigang Wu, Alun Li, Fengli Zhao, Hu Feng, Lulu Ding, Jue Ruan
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-019-6337-2