Ligustilide Ameliorates Memory Deficiency in APP/PS1 Transgenic Mice via Restoring Mitochondrial Dysfunction

Ligustilide, the main lipophilic component of Radix angelicae sinensis, has been shown to ameliorate cognitive dysfunction in a few Alzheimer’s disease mouse models, but its mechanism is not fully understood. In this study, we employed 7-month-old APP/PS1 mice to explore whether LIG is able to prote...

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Bibliographic Details
Main Authors: Yi-Jun Xu, Yu Mei, Zi-Ling Qu, Shi-Jie Zhang, Wei Zhao, Jian-Song Fang, Jun Wu, Cong Yang, Si-Jun Liu, Yong-Qi Fang, Qi Wang, Yong-Bin Zhang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/4606752