The Efficacy of Posttreatment with Synthetic C-Reactive Protein in Murine Bacterial Peritonitis via Activation of FcγRI-Expressing Kupffer Cells

The Efficacy of Posttreatment with Synthetic C-Reactive Protein in Murine Bacterial Peritonitis via Activation of FcγRI-Expressing Kupffer Cells

Pretreatment with synthetic C-reactive protein (CRP), a functional CRP peptide, has the potential to augment macrophage phagocytosis by bacterial challenge. However, the posttreatment is clinically ideal. We investigated the efficacy of posttreatment with synthetic CRP on murine cecal ligation and p...

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Bibliographic Details
Main Authors: Manabu Kinoshita, Seigo Ito, Takuya Ishikiriyama, Kumiko Sekiguchi, Ryota Yamaguchi, Ryoichi Tsuruhara, Akihisa Matsuda, Kazuki Koiwa, Masahiro Nakashima, Hiroyuki Nakashima, Masao Miyashita, Shuhji Seki
Format: Article
Language:English
Published: Karger Publishers 2021-05-01
Series:Journal of Innate Immunity
Subjects:
cecal ligation and puncture
liver macrophages
phagolysosomal activity
Online Access:https://www.karger.com/Article/FullText/515333

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