Metabolomics analysis of follicular fluid coupled with oocyte aspiration reveals importance of glucocorticoids in primate periovulatory follicle competency

Abstract Gonadotropin administration during infertility treatment stimulates the growth and development of multiple ovarian follicles, yielding heterogeneous oocytes with variable capacity for fertilization, cleavage, and blastocyst formation. To determine how the intrafollicular environment affects...

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Bibliographic Details
Main Authors: Sweta Ravisankar, Kelsey E. Brooks, Melinda J. Murphy, Nash Redmayne, Junghyun Ryu, Jason M. Kinchen, Shawn L. Chavez, Jon D. Hennebold
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85704-6