Integrase and integration: biochemical activities of HIV-1 integrase

<p>Abstract</p> <p>Integration of retroviral DNA is an obligatory step of retrovirus replication because proviral DNA is the template for productive infection. Integrase, a retroviral enzyme, catalyses integration. The process of integration can be divided into two sequential react...

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Bibliographic Details
Main Authors: Deprez Eric, Saïb Ali, Carayon Kevin, Delelis Olivier, Mouscadet Jean-François
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/114