Osmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.

Osmotic stress changes the expression and subcellular localization of the Batten disease protein CLN3.

Juvenile CLN3 disease (formerly known as juvenile neuronal ceroid lipofuscinosis) is a fatal childhood neurodegenerative disorder caused by mutations in the CLN3 gene. CLN3 encodes a putative lysosomal transmembrane protein with unknown function. Previous cell culture studies using CLN3-overexpressi...

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Bibliographic Details
Main Authors: Amanda Getty, Attila D Kovács, Tímea Lengyel-Nelson, Andrew Cardillo, Caitlin Hof, Chun-Hung Chan, David A Pearce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688782?pdf=render

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http://europepmc.org/articles/PMC3688782?pdf=render

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