Immunosuppressive microenvironment in neuroblastoma

Immunosuppressive microenvironment in neuroblastoma

According to the cancer immunoediting model, the interplay between tumor cells and the host immune system is crucial for the control of tumor growth. NB is a pediatric tumor that presents with metastatic disease at diagnosis in about 50% of the cases, the majority of which have poor prognosis. In th...

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Bibliographic Details
Main Authors: Vito ePistoia, Fabio eMorandi, Giovanna eBianchi, Annalisa ePezzolo, Ignazia ePrigione, Lizzia eRaffaghello
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Oncology
Subjects:
neuroblastoma microenvironment
immunosuppressive mechanisms
antigen processing machinery defects
neuroblastoma derived immunosuppressive molecules
tumor microenvironment targeting
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00167/full

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http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00167/full

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