Low CD40 Expression Levels in Infantum-Infected Bone Marrow Dendritic Cells Evoke Regulatory Responses by Down-Regulating Interleukin-12 Production: Role of ERK1/2
Dendritic cells (DCs) play a pivotal role in promoting resistance to leishmaniasis, both by activating CD4 + T cells and endorsing their differentiation into Th1 cells by producing interleukin (IL)-12. High level of IL-12 production, a decisive component of the DC maturation, requires not only micro...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-05-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/1721727X1401200211 |