Continuous Adaptive Evolution of a Fast-Growing Corynebacterium glutamicum Strain Independent of Protocatechuate

Continuous Adaptive Evolution of a Fast-Growing Corynebacterium glutamicum Strain Independent of Protocatechuate

Corynebacterium glutamicum is a commonly applied host for the industrial production of amino acids. While valued for its robustness, it is somewhat inferior to competing strains such as Escherichia coli because of the relatively low growth rate of 0.40 h−1 in synthetic, industrial media. Accordingly...

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Bibliographic Details
Main Authors: Michaela Graf, Thorsten Haas, Felix Müller, Anina Buchmann, Julia Harm-Bekbenbetova, Andreas Freund, Alexander Nieß, Marcus Persicke, Jörn Kalinowski, Bastian Blombach, Ralf Takors
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
Corynebacterium glutamicum
adaptive laboratory evolution
continuous adaptive evolution
increased growth
protocatechuate
RamA
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01648/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01648/full

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