The Past, Present, and Future of Human Centromere Genomics
The centromere is the chromosomal locus essential for chromosome inheritance and genome stability. Human centromeres are located at repetitive alpha satellite DNA arrays that compose approximately 5% of the genome. Contiguous alpha satellite DNA sequence is absent from the assembled reference genome...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-01-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/5/1/33 |