Development and validation of a rapid chromatographic method for the analysis of flunarizine and its main production impurities

A rapid selective method for the analysis of flunarizine and its associated impurities was developed and validated according to ICH guidelines. The separation was carried out using a Thermo Scientific Hypersil Gold C18 column (50mmÃ4.6mm i.d., 1.9μm particle size) with a gradient mobile phase of ac...

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Bibliographic Details
Main Authors: Niamh OâConnor, Michael Geary, Mary Wharton, Paul Sweetman
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177912001463