USP14 as a Therapeutic Target Against Neurodegeneration: A Rat Brain Perspective

In the recent past, many of the deubiquitinases (DUB) were found to modulate mitochondrial clearance or mitophagy and thus they are currently projected as therapeutic targets against neurodegeneration. Among these DUBs, USP14 stands at a distinctive juncture, since it can influence both proteasome c...

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Bibliographic Details
Main Authors: Chayan Banerjee, Moumita Roy, Rupsha Mondal, Joy Chakraborty
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00727/full