Efficient error correction for next-generation sequencing of viral amplicons

<p>Abstract</p> <p>Background</p> <p>Next-generation sequencing allows the analysis of an unprecedented number of viral sequence variants from infected patients, presenting a novel opportunity for understanding virus evolution, drug resistance and immune escape. However...

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Bibliographic Details
Main Authors: Skums Pavel, Dimitrova Zoya, Campo David S, Vaughan Gilberto, Rossi Livia, Forbi Joseph C, Yokosawa Jonny, Zelikovsky Alex, Khudyakov Yury
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Bioinformatics