Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells.
Cellular metabolism plays a critical role in regulating T cell responses and the development of memory T cells with long-term protections. However, the metabolic phenotype of antigen-activated T cells that are responsible for the generation of long-lived memory cells has not been characterized.Using...
Main Authors: | Shan He, Koji Kato, Jiu Jiang, Daniel R Wahl, Shin Mineishi, Erin M Fisher, Donna M Murasko, Gary D Glick, Yi Zhang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3096660?pdf=render |
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