Tigecycline Interferes with Fibrinogen Polymerization Independent of Peripheral Interactions with the Coagulation System

Tigecycline Interferes with Fibrinogen Polymerization Independent of Peripheral Interactions with the Coagulation System

Tigecycline offers broad anti-bacterial coverage for critically ill patients with complicated infections. A described but less researched side effect is coagulopathy. The aim of this study was to test whether tigecycline interferes with fibrinogen polymerization by peripheral interactions. To study...

Full description

Bibliographic Details
Main Authors: Anna Brandtner, Mirjam Bachler, Dietmar Fries, Martin Hermann, Jacqueline Ruehlicke, Vilmos Fux, Andrea Griesmacher, Christian Niederwanger, Tobias Hell, Benedikt Treml
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Antibiotics
Subjects:
tigecycline
fibrinogen
bleeding
real time live confocal analysis
hepatocyte cell culture
Online Access:https://www.mdpi.com/2079-6382/9/2/84

Internet

https://www.mdpi.com/2079-6382/9/2/84

Similar Items