Cytoskeletal rearrangements in synovial fibroblasts as a novel pathophysiological determinant of modeled rheumatoid arthritis.

Rheumatoid arthritis is a chronic inflammatory disease with a high prevalence and substantial socioeconomic burden. Despite intense research efforts, its aetiology and pathogenesis remain poorly understood. To identify novel genes and/or cellular pathways involved in the pathogenesis of the disease,...

Full description

Bibliographic Details
Main Authors: Vassilis Aidinis, Piero Carninci, Maria Armaka, Walter Witke, Vaggelis Harokopos, Norman Pavelka, Dirk Koczan, Christos Argyropoulos, Maung-Maung Thwin, Steffen Möller, Kazunori Waki, Ponnampalam Gopalakrishnakone, Paola Ricciardi-Castagnoli, Hans-Jürgen Thiesen, Yoshihide Hayashizaki, George Kollias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1270006?pdf=render