A Computational Model of Quantitative Chromatin Immunoprecipitation (ChIP) Analysis

Chromatin immunoprecipitation (ChIP) analysis is widely used to identify the locations in genomes occupied by transcription factors (TFs). The approach involves chemical cross-linking of DNA with associated proteins, fragmentation of chromatin by sonication or enzymatic digestion, immunoprecipitatio...

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Bibliographic Details
Main Authors: Jingping Xie, Philip S. Crooke, Brett A. McKinney, Joel Soltman, Stephen J. Brandt M.D.
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S295