Investigating the relationship between BMI across adulthood and late life brain pathologies

Abstract Background In view of reported associations between high adiposity, particularly in midlife and late-life dementia risk, we aimed to determine associations between body mass index (BMI), and BMI changes across adulthood and brain structure and pathology at age 69–71 years. Methods Four hund...

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Bibliographic Details
Main Authors: Christopher A. Lane, Josephine Barnes, Jennifer M. Nicholas, John W. Baker, Carole H. Sudre, David M. Cash, Thomas D. Parker, Ian B. Malone, Kirsty Lu, Sarah-Naomi James, Ashvini Keshavan, Sarah Buchanan, Sarah Keuss, Heidi Murray-Smith, Andrew Wong, Elizabeth Gordon, William Coath, Marc Modat, David Thomas, Rebecca Hardy, Marcus Richards, Nick C. Fox, Jonathan M. Schott
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
MRI
PET
Online Access:https://doi.org/10.1186/s13195-021-00830-7