Controlled Drug Release and Cytotoxicity Studies of Beta-Lapachone and Doxorubicin Loaded into Cyclodextrins Attached to a Polyethyleneimine Matrix

Controlled Drug Release and Cytotoxicity Studies of Beta-Lapachone and Doxorubicin Loaded into Cyclodextrins Attached to a Polyethyleneimine Matrix

This work presents a new look at the application of cyclodextrins (CD) as a drug nanocarrier. Two different cyclodextrins (<i>α</i>CD, <i>β</i>CD) were covalently conjugated to branched polyethylenimine (PEI), which was additionally functionalized with folic acid (PEI-<i&g...

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Bibliographic Details
Main Authors: Agata Kowalczyk, Artur Kasprzak, Magdalena Poplawska, Monika Ruzycka, Ireneusz P. Grudzinski, Anna M. Nowicka
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
controlled drug release
cyclodextrin
lapachone
doxorubicin
polyethylenimine
cytotoxicity studies
Online Access:https://www.mdpi.com/1422-0067/21/16/5832

Internet

https://www.mdpi.com/1422-0067/21/16/5832

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