Potent Neutralization Ability of a Human Monoclonal Antibody Against Serotype 1 Dengue Virus

Potent Neutralization Ability of a Human Monoclonal Antibody Against Serotype 1 Dengue Virus

The incidence of dengue virus (DENV) infections has been escalating in tropical and subtropical countries, but there are still no effective therapeutic options. In the present study, a DENV-1-specific human monoclonal antibody (HMAb), 1G5, isolated from single plasma cells obtained from the peripher...

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Bibliographic Details
Main Authors: Jiansheng Lu, Rong Wang, Binghui Xia, Yunzhou Yu, Xiaowei Zhou, Zhixin Yang, Peitang Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
human monoclonal antibody
1G5
dengue virus serotype 1
envelope protein
antibody-dependent enhancement
antibody neutralization
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01214/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01214/full

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