Studies on pharmacokinetic properties and absorption mechanism of phloretin: In vivo and in vitro

Phloretin is a natural dihydrochalcone flavonoid that is mainly distributed in apple, pear and other juicy fruit peels or root peels. Phloretin exhibits several pharmacological properties, such as antidiabetic, antioxidant, anti-inflammatory, and antitumor activities. However, the poor water solubil...

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Bibliographic Details
Main Authors: Yuan yuan Zhao, Yu Fan, Mei Wang, Jing Wang, Jiang xue Cheng, Jun bo Zou, Xiao fei Zhang, Ya jun Shi, Dong yan Guo
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220310027