Insights into CYP2B6-mediated drug–drug interactions

Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug metabolism than was previously believed. The discovery of multiple important substrates of CYP2B6 as well as polymorphic differences has sparked increasing interest in the genetic and xenobiotic factors contributing to...

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Bibliographic Details
Main Authors: William D. Hedrich, Hazem E. Hassan, Hongbing Wang
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Acta Pharmaceutica Sinica B
Subjects:
CAR
PXR
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383516302532