Human Tau isoform-specific presynaptic deficits in a Drosophila Central Nervous System circuit

Accumulation of normal or mutant human Tau isoforms in Central Nervous System (CNS) neurons of vertebrate and invertebrate models underlies pathologies ranging from behavioral deficits to neurodegeneration that broadly recapitulate human Tauopathies. Although some functional differences have begun t...

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Bibliographic Details
Main Authors: Dimitrios Kadas, Katerina Papanikolopoulou, Sofia Xirou, Christos Consoulas, Efthimios M.C. Skoulakis
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118307587