Dynamic constriction and fission of endoplasmic reticulum membranes by reticulon

The endoplasmic reticulum (ER) is an intracellular network characterized by highly dynamic behavior whose control mechanisms are unclear. Here, the authors show that the ER-membrane protein Reticulon (Rtnl1) can constrict ER bilayers and lead to ER fission.

Bibliographic Details
Main Authors: Javier Espadas, Diana Pendin, Rebeca Bocanegra, Artur Escalada, Giulia Misticoni, Tatiana Trevisan, Ariana Velasco del Olmo, Aldo Montagna, Sergio Bova, Borja Ibarra, Peter I. Kuzmin, Pavel V. Bashkirov, Anna V. Shnyrova, Vadim A. Frolov, Andrea Daga
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13327-7