Selection upon genome architecture: conservation of functional neighborhoods with changing genes.

An increasing number of evidences show that genes are not distributed randomly across eukaryotic chromosomes, but rather in functional neighborhoods. Nevertheless, the driving force that originated and maintains such neighborhoods is still a matter of controversy. We present the first detailed multi...

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Bibliographic Details
Main Authors: Fátima Al-Shahrour, Pablo Minguez, Tomás Marqués-Bonet, Elodie Gazave, Arcadi Navarro, Joaquín Dopazo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2951340?pdf=render